SENIOR/PRINCIPAL SCIENTIST, SYNTHETIC ORGANIC CHEMISTRY

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Oct 15, 2021 | Jobs | Other | Tel Aviv / Mercaz
SENIOR/PRINCIPAL SCIENTIST, SYNTHETIC ORGANIC CHEMISTRY
Full Time

A great opportunity to join the core team of a fast-growing startup: join DeepCure and have a massive impact on redefining drug discovery. DeepCure is searching for a creative, resourceful, and integrative thinker for an important role in our automated chemistry group. As a senior/principal scientist, you will join a team at the heart of applying our transformative Artificial Intelligence (AI) platform to discovering novel therapeutics. The successful candidate will plan and implement creative scientific research through conducting laboratory experiments whilst also being given opportunities to be involved in our discovery team. This may include timeline and resource planning, reviewing, analyzing, and interpreting scientific data, and providing regular updates with critical input on project results.This is a strategic growth area of critical importance for DeepCure and you will have fantastic support from a team of outstanding scientists and AI experts along with dedicated facilities. You will also be able to interact with project teams and see real-world impact across our portfolio of drug discovery projects to benefit patients.

More about DeepCure:
DeepCure is a next-generation therapeutics company, built from the ground up with equal importance to computation and life-sciences. Our mission is to deliver to patients safer and more efficacious therapeutics that are extremely unlikely to be discovered by traditional drug discovery pipelines. We are a team of curious, multidisciplinary, and impact-driven professionals on a quest to redefine the way drugs are discovered.
We are currently building our DeepCure Israel team, which will be based in the Rehovot Science Park, to establish and run the lab operations in our cutting-edge automated lab. The Israeli team will collaborate closely with our global team on the exciting challenges on our way to revolutionizing the drug discovery industry.

In this role you will:

    • Independently synthesis and characterize high-quality intermediates and bioactive compounds utilizing our AI platform-tools
    • Help build our automated synthesis platform to complement our AI platform by synthesizing subsets of computationally enumerated libraries
    • Support our medicinal chemistry efforts through providing synthetic routes, interacting with CRO’s, and providing critical analysis of complete targets
    • Create and execute strategies to protect and expand intellectual property whilst developing new approaches to the expansion of known chemical space
    • Makes broad scientific contributions that have an impact on the research direction of the company
    • Proactively investigate new or different technologies to improve the effectiveness of the drug discovery process

Basic qualifications:

    • MS in organic chemistry and 2+ years of relevant industrial experience or doctoral degree (Ph.D.) or equivalent in synthetic organic chemistry or medicinal chemistry
    • Scientific expertise in organic chemistry, knowledge of modern literature, in-depth exposure to a wide range of purification and spectroscopic characterization techniques, and the ability to champion new chemistry directions
    • Strong collaboration skills, with the ability to work effectively within a diverse team of internal and external co-workers.

Preferred qualifications:

    • Excitement about the vision and mission of DeepCure to redefine drug discovery through innovation
    • Deep expertise in modern synthetic organic chemistry with excitement to innovate using automation
    • Experienced in the use of synthetic chemistry instrumentation: HPLC, LC-MS, NMR, and purification systems
    • Expert in using common medicinal chemistry software: electronic notebook, ChemDraw, Excel; Data visualization; structure viewing; chemical and database searching
    • A strong publication record evidencing scientific curiosity and strong communication skills
    • Ability and desire to work collaboratively on complex problems – Engaged with a diverse group of scientists, integrating data from multiple disciplines.
    • Experience in small molecule drug discovery in a biotech or pharmaceutical setting

Benefits:
For the right candidate, we'll offer a competitive salary and a generous equity grant. Your compensation is rounded out by a strong benefits package:
* A leadership team that values and prioritizes your professional development* Flexible work hours* Unlimited paid leave and sick time* Lunch subsidies * Transportation expenses/parking* Work in a cool and vibrant space at the heart of Rehovot Science Park* Have the opportunity to work with an international team of innovative scientists across different disciplines.
“Brainstorming on my challenges with all these amazing brains deserves a shout-out every sprint” (Jon, Member of our Machine learning team).
Most importantly, you'll have a huge impact, do important work, and work with a team of people you'll genuinely enjoy spending the day with.
DeepCure is an equal opportunity employer, dedicated to creating a workplace that is free of harassment and discrimination. We base our employment decisions on business needs, job requirements, and qualifications — that's all. We do not discriminate based on race, gender, religion, health, personal beliefs, age, family or parental status, or any other status. We don't tolerate any kind of discrimination or bias, and we are looking for teammates who feel the same way.APPLY FOR THIS JOB


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